AI designs drugs

Human trials begin for a drug designed entirely by AI.

By AI Guy ⏳ 4 min read

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In Today’s edition:

💊 Human trials begin for a drug designed by AI

🇬🇧 Google Deepmind’s CEO attempts to out-design ChatGpt

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Human Trials begin for a drug designed entirely by AI 💊 

Insilico Medicine, a biotech company based in Hong Kong, says its trial of lung disease therapy using an AI-developed drug is a milestone for generative AI.

(Left) Zhavoronkov - CEO of Insilico, (Right) Feng Ren - Chief Science Officer

Insilico said the drug, INS018_055, will be the first entirely “AI-discovered and AI-designed” drug in history to begin a phase 2 clinical trial.

Insilico is one of a new generation of biotechs that has raised billions in new funding for AI drug development. The market for AI in the drug market is estimated to be around $50 billion.

“For Insilico, it is the moment of truth . . . but it is also a true test for AI and the entire industry should be watching”

Zhavoronkov – CEO of Insilico

Insilico’s AI platforms could potentially halve the time it takes to discover drugs and greatly reduce the cost of bringing new drugs to market. Deloitte estimated the platform could save $2.3bn on average per therapy. Several big pharma companies including names like Johnson & Johnson have signed partnership deals with Insilico to access the technology.

The heart of the AI platform is its ability to analyze vast amounts of data to rapidly identify drug targets and identify molecules that can be made into medicines. Insilico’s AI could save two to four years in pre-clinical discovery depending on the novelty and complexity of the target.

Insilico conducted its phase 1 trials of INS018_055 in New Zealand and China which had favorable results. The second phase of the trial will study the tolerability and preliminary efficacy of the drug.

Dr. Grover would be proud.

Google Deepmind’s CEO claims their next product will outperform ChatGPT 📈 👨‍💻

Google DeepMind’s AI lab made history in 2016 by developing an AI bot, dubbed AlphaGo, that could defeat champion players in board games.

Now, Deepmind’s founder and CEO, Demis Hassabis, says his engineers are using the same framework from AlphaGo to build an AI model that is far more capable that OpenAI’s ChatGPT. The company calls this new product “Gemini”.

“At a high level you can think of Gemini as combining some of the strengths of AlphaGo-type systems with the amazing language capabilities of the large models”

Demis Hassabis – CEO of DeepMind

AlphaGo was based on a method called tree search to explore and remember possible moves on the board. The next step for DeepMind in developing a ChatGPT-style model would involve performing more tasks and exploring more possibilities on the internet.

It will take a number of months and millions of dollars to complete the development of Gemini, but Hassabis is optimistic about its capabilities. Each version of an AI model requires feeding vasts amounts of data into the model, which can come at a high cost. Sam Altman said OpenAI’s GPT-4 version cost roughly $100 million to develop.

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AI Art 🎨

A raccoon playing tennis at Wimbledon in the 1990s

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